ARTICLE
The role of alcoholic extract of Zataria multiflora Boiss in controlling opium withdrawal symptoms: a randomized, double-blind study
| 1 | Psychiatrist, Associate Professor, Faculty member of Jundishapur University, Ahvaz, Iran. |
| 2 | 2. Associated professor , faculty member Medicinal Plant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran |
| 3 | Apadana clinical research center |
CORRESPONDING AUTHOR
Submission date: 2017-02-05
Final revision date: 2017-05-29
Acceptance date: 2017-06-02
Publication date: 2017-09-30
Arch Psych Psych 2017;19(3):27–33
KEYWORDS
TOPICS
ABSTRACT
Aim of the study:
The effect of the alcoholic extract of Zataria multiflora Boiss in controlling the symptoms of opium withdrawal compared to methadone was studied.
Subject or material and methods:
In a double-blind, randomized clinical trial, alcoholic extract of Zataria multiflora Boiss and methadone were given to 40 patients and withdrawal symptoms in the days of 0,2,7,11 and 15 was evaluated by the CINA scale.
Results:
Withdrawal symptoms were controlled in both study groups and these symptoms were tolerated when reducing the methadone dose in the theme group.
Discussion:
Herbs have been used to treat various diseases, especially chronic and treatment-resistant diseases in countries with a long and traditional culture. Thus, if this is done in no systematic and structured manner, it can be problematic for patients and health systems.
Conclusions:
Alcoholic extract of Zataria multiflora Boiss can be used as an effective agent in controlling the symptoms of opium withdrawal that need to be considered in future studies.
The effect of the alcoholic extract of Zataria multiflora Boiss in controlling the symptoms of opium withdrawal compared to methadone was studied.
Subject or material and methods:
In a double-blind, randomized clinical trial, alcoholic extract of Zataria multiflora Boiss and methadone were given to 40 patients and withdrawal symptoms in the days of 0,2,7,11 and 15 was evaluated by the CINA scale.
Results:
Withdrawal symptoms were controlled in both study groups and these symptoms were tolerated when reducing the methadone dose in the theme group.
Discussion:
Herbs have been used to treat various diseases, especially chronic and treatment-resistant diseases in countries with a long and traditional culture. Thus, if this is done in no systematic and structured manner, it can be problematic for patients and health systems.
Conclusions:
Alcoholic extract of Zataria multiflora Boiss can be used as an effective agent in controlling the symptoms of opium withdrawal that need to be considered in future studies.
Project no. RCN/SN/0189/2021/1 implemented from 2022 to 2024
Total value of the project: PLN 200 000
Amount funded by the MEiN: PLN 80 000
Aims of the project: Publication in Open Access mode on the Internet of 8 consecutive issues of the journal Archives of Psychiatry and Psychotherapy (years 2022-2024). Modernization and redesign of the journal’s website. Financing of the Editorial System. Copy editing and proofreading of journal issues. Counteracting scientific misinformation. Submission of electronic versions of the journal to the National Digital Library Polona and the Digital Library of Scientific Publications Academica.
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